Install the Splunk Universal forwarder and point it at the file. If you want to do some predictions and anomaly detection check out the predict command (I think it was introduced in Splunk 6.0). http://docs.splunk.com/Documentation/Splunk/6.0/SearchReference/Predict
Here is an example of how I am using the predict command in order to determine when Symantec detects more viruses/hour than normal:
index=symantec (virus OR "security risk" OR "web attack") NOT "Tracking Cookies" earliest=-21d@d latest=now | rex "(?i) name: (?P [^,]+)" | bucket span=1h _time | timechart span=1h count(virus_host) as count | predict count | rename upper95(prediction(count)) as upper95 | fieldformat upper95=round(upper95,0) | sort -_time | eval Percent=round(upper95/count*100,0) | eval PercentAbove95thPecentile=round(100-Percent,0) | fields - Percent,lower95(prediction(count)),prediction(count) | fillnull value=0 count PercentAbove95thPecentile | head 10 | where PercentAbove95thPecentile>=1
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